Showing entry for Protein mono-ADP-ribosyltransferase PARP10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015012
Protein NameProtein mono-ADP-ribosyltransferase PARP10
Uniport IdQ53GL7
GenePARP10
Gene Id84875
DomainPARP
Pfam PF00644  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
Biological Process GO:0048147 negative regulation of fibroblast proliferation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:1900045 negative regulation of protein K63-linked ubiquitination
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:0006471 protein ADP-ribosylation
Biological Process GO:0070213 protein auto-ADP-ribosylation
Biological Process GO:0140289 protein mono-ADP-ribosylation
Biological Process GO:0070212 protein poly-ADP-ribosylation
Biological Process GO:0010847 regulation of chromatin assembly
Biological Process GO:0019985 translesion synthesis
molecular function GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
molecular function GO:0003950 NAD+ ADP-ribosyltransferase activity
molecular function GO:1990404 protein ADP-ribosylase activity
molecular function GO:0003714 transcription corepressor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-196807 Nicotinate metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-197264 Nicotinamide salvaging
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-9678108 SARS-CoV-1 Infection
R-HSA-9679506 SARS-CoV Infections
R-HSA-9679506 SARS-CoV Infections
R-HSA-9683610 Maturation of nucleoprotein
R-HSA-9683701 Translation of structural proteins
R-HSA-9694516 SARS-CoV-2 Infection
R-HSA-9694631 Maturation of nucleoprotein
R-HSA-9694635 Translation of structural proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236773 BXGD004827 Depressed bipolar I disorder Mental Disorders
C0337428 BXGD007155 Fibrinogen assay
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0427460 BXGD008616 Red cell distribution width determination
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0744869 BXGD010109 Metastatic hepatocellular carcinoma Digestive System Diseases; Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0006198 Citric acid 192.12
BXGC0020637 4-hydroxybenzamide 137.05
BXGC0038633 3-Methoxycinnamic acid 178.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein