protein

Showing entry for Bifunctional dihydrofolate reductase-thymidylate synthase

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT015184
Protein Name	Bifunctional dihydrofolate reductase-thymidylate synthase
Uniport Id	Q582G3
Gene	Tb927.7.5480
Gene Id	3658761
Domain	DHFR_1; Thymidylat_synt
Pfam	PF00186 PF00303
Organism	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006231	dTMP biosynthetic process
Biological Process	GO:0006545	glycine biosynthetic process
Biological Process	GO:0032259	methylation
Biological Process	GO:0009165	nucleotide biosynthetic process
Biological Process	GO:0006730	one-carbon metabolic process
Biological Process	GO:0010608	posttranscriptional regulation of gene expression
Biological Process	GO:0046654	tetrahydrofolate biosynthetic process
Biological Process	GO:0046105	thymidine biosynthetic process
molecular function	GO:0004146	dihydrofolate reductase activity
molecular function	GO:0004799	thymidylate synthase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0005739	mitochondrion

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0042188	1H-Benzimidazol-2-Amine		133.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}