Showing entry for Serine/threonine-protein kinase TNNI3K


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015278
Protein NameSerine/threonine-protein kinase TNNI3K
Uniport IdQ59H18
GeneTNNI3K
Gene Id100526835;51086
DomainAnk_2; Ank_4; Pkinase_Tyr
Pfam PF12796   PF07714  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086069 bundle of His cell to Purkinje myocyte communication
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:1903779 regulation of cardiac conduction
Biological Process GO:0055117 regulation of cardiac muscle contraction
Biological Process GO:0002027 regulation of heart rate
molecular function GO:0005524 ATP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0031013 troponin I binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001486 BXGD000056 Adenovirus Infections Infections
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004239 BXGD000263 Atrial Flutter Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005893 BXGD000346 Body mass index procedure
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008928 BXGD000576 Cleidocranial Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030590 BXGD002246 Paroxysmal supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0033626 BXGD002412 Protein Deficiency Nutritional and Metabolic Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0039240 BXGD002804 Supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085610 BXGD003202 Sinus bradycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0085611 BXGD003203 Atrial arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085615 BXGD003206 Right bundle branch block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151636 BXGD003451 Premature ventricular contractions Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0264912 BXGD005435 Left anterior fascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0562350 BXGD009476 Hip circumference
C0578022 BXGD009541 Finding of body mass index
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596887 BXGD009648 mathematical ability
C0751951 BXGD010648 Central Core Myopathy (disorder) Musculoskeletal Diseases; Nervous System Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1305855 BXGD012348 Body mass index
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1560305 BXGD013362 Prolonged QTc interval
C1611743 BXGD013456 Familial (FPAH)
C1963175 BXGD016687 Sinus Bradycardia, CTCAE
C1963217 BXGD016689 Prolonged QTc Interval, CTCAE
C2108093 BXGD016919 continuous electrocardiogram - paroxysmal supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2108107 BXGD016920 continuous electrocardiogram sinus bradycardia (finding)
C2215995 BXGD016947 electrocardiogram - left anterior hemiblock
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C3495676 BXGD019000 Anorectal Malformations Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4015285 BXGD020197 CARDIAC CONDUCTION DISEASE WITH OR WITHOUT DILATED CARDIOMYOPATHY
C4049938 BXGD021956 Physical Activity Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein