Showing entry for E3 ubiquitin-protein ligase ZNRF3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015842
Protein NameE3 ubiquitin-protein ligase ZNRF3
Uniport IdQ5SSZ7
GeneZnrf3
Gene Id407821
Domainzf-RING_2; ZNRF_3_ecto
Pfam PF13639   PF18212  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060173 limb development
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:2000051 negative regulation of non-canonical Wnt signaling pathway
Biological Process GO:0030178 negative regulation of Wnt signaling pathway
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0060828 regulation of canonical Wnt signaling pathway
Biological Process GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway
Biological Process GO:0072089 stem cell proliferation
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
Biological Process GO:0038018 Wnt receptor catabolic process
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0005109 frizzled binding
molecular function GO:0046872 metal ion binding
molecular function GO:0061630 ubiquitin protein ligase activity
molecular function GO:0004842 ubiquitin-protein transferase activity
cellular component GO:0005887 integral component of plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0006368 Formic acid 46.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein