Showing entry for Tyrosyl-DNA phosphodiesterase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015909
Protein NameTyrosyl-DNA phosphodiesterase 2
Uniport IdQ5XJA0
Genetdp2
Gene Id553516
DomainExo_endo_phos
Pfam PF03372  
OrganismDanio rerio (Zebrafish) (Brachydanio rerio)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060027 convergent extension involved in gastrulation
Biological Process GO:0007368 determination of left/right symmetry
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0007369 gastrulation
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
molecular function GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity
molecular function GO:0003677 DNA binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0004518 nuclease activity
molecular function GO:0003697 single-stranded DNA binding
molecular function GO:0070259 tyrosyl-DNA phosphodiesterase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005654 nucleoplasm
cellular component GO:0016605 PML body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein