Showing entry for Macrophage receptor MARCO


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015997
Protein NameMacrophage receptor MARCO
Uniport IdQ60754
GeneMarco
Gene Id17167
DomainCollagen; SRCR
Pfam PF01391   PF00530  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:0043277 apoptotic cell clearance
Biological Process GO:0006897 endocytosis
Biological Process GO:0045087 innate immune response
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0006898 receptor-mediated endocytosis
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0038024 cargo receptor activity
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0005044 scavenger receptor activity
cellular component GO:0005581 collagen trimer
cellular component GO:0005737 cytoplasm
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein