Showing entry for E3 ubiquitin/ISG15 ligase TRIM25


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016019
Protein NameE3 ubiquitin/ISG15 ligase TRIM25
Uniport IdQ61510
GeneTrim25
Gene Id217069
DomainPRY; SPRY; zf-C3HC4_4
Pfam PF13765   PF00622  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0051607 defense response to virus
Biological Process GO:0045087 innate immune response
Biological Process GO:0046597 negative regulation of viral entry into host cell
Biological Process GO:1902187 negative regulation of viral release from host cell
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0006513 protein monoubiquitination
Biological Process GO:0046596 regulation of viral entry into host cell
Biological Process GO:1902186 regulation of viral release from host cell
Biological Process GO:0043627 response to estrogen
Biological Process GO:0033280 response to vitamin D
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0016874 ligase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0039552 RIG-I binding
molecular function GO:0061630 ubiquitin protein ligase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0010494 cytoplasmic stress granule
cellular component GO:0005829 cytosol
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein