Showing entry for Neuroligin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016042
Protein NameNeuroligin-1
Uniport IdQ62765
GeneNlgn1
Gene Id116647
DomainCOesterase
Pfam PF00135  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097113 AMPA glutamate receptor clustering
Biological Process GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0048789 cytoskeletal matrix organization at active zone
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:1904861 excitatory synapse assembly
Biological Process GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0061002 negative regulation of dendritic spine morphogenesis
Biological Process GO:0007399 nervous system development
Biological Process GO:0097115 neurexin clustering involved in presynaptic membrane assembly
Biological Process GO:0045161 neuronal ion channel clustering
Biological Process GO:0007158 neuron cell-cell adhesion
Biological Process GO:0140058 neuron projection arborization
Biological Process GO:0031175 neuron projection development
Biological Process GO:0097114 NMDA glutamate receptor clustering
Biological Process GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness
Biological Process GO:0060999 positive regulation of dendritic spine development
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:1902533 positive regulation of intracellular signal transduction
Biological Process GO:1905520 positive regulation of presynaptic active zone assembly
Biological Process GO:1902474 positive regulation of protein localization to synapse
Biological Process GO:1900029 positive regulation of ruffle assembly
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0032230 positive regulation of synaptic transmission, GABAergic
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:2000809 positive regulation of synaptic vesicle clustering
Biological Process GO:1900244 positive regulation of synaptic vesicle endocytosis
Biological Process GO:2000302 positive regulation of synaptic vesicle exocytosis
Biological Process GO:0097119 postsynaptic density protein 95 clustering
Biological Process GO:0097104 postsynaptic membrane assembly
Biological Process GO:0098698 postsynaptic specialization assembly
Biological Process GO:0097105 presynaptic membrane assembly
Biological Process GO:0035418 protein localization to synapse
Biological Process GO:0006605 protein targeting
Biological Process GO:0097120 receptor localization to synapse
Biological Process GO:2000311 regulation of AMPA receptor activity
Biological Process GO:0045664 regulation of neuron differentiation
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0002087 regulation of respiratory gaseous exchange by nervous system process
Biological Process GO:0098942 retrograde trans-synaptic signaling by trans-synaptic protein complex
Biological Process GO:0048511 rhythmic process
Biological Process GO:0007416 synapse assembly
Biological Process GO:0050808 synapse organization
Biological Process GO:0099560 synaptic membrane adhesion
Biological Process GO:0097091 synaptic vesicle clustering
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016080 synaptic vesicle targeting
Biological Process GO:0048489 synaptic vesicle transport
Biological Process GO:0072553 terminal button organization
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0042802 identical protein binding
molecular function GO:0042043 neurexin family protein binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0038023 signaling receptor activity
cellular component GO:0009986 cell surface
cellular component GO:0030425 dendrite
cellular component GO:0043198 dendritic shaft
cellular component GO:0043197 dendritic spine
cellular component GO:0060076 excitatory synapse
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0032433 filopodium tip
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098793 presynapse
cellular component GO:0043235 receptor complex
cellular component GO:0045202 synapse
cellular component GO:0043083 synaptic cleft
cellular component GO:0097060 synaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein