Showing entry for Disks large homolog 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016050
Protein NameDisks large homolog 3
Uniport IdQ62936
GeneDlg3
Gene Id58948
DomainGuanylate_kin; MAGUK_N_PEST; PDZ; PDZ_assoc; SH3_1
Pfam PF00625   PF10608   PF00595   PF10600   PF00018  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0001736 establishment of planar polarity
Biological Process GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
Biological Process GO:0010923 negative regulation of phosphatase activity
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:0043113 receptor clustering
Biological Process GO:0097120 receptor localization to synapse
Biological Process GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0019900 kinase binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0019902 phosphatase binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0098919 structural constituent of postsynaptic density
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0032281 AMPA glutamate receptor complex
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005911 cell-cell junction
cellular component GO:0030054 cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0043198 dendritic shaft
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0030426 growth cone
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0099092 postsynaptic density, intracellular component
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein