protein

Showing entry for Progesterone receptor

General Target Information
BXGT Id	BXGT016072
Protein Name	Progesterone receptor
Uniport Id	Q63449
Gene	Pgr
Gene Id	25154
Domain	Hormone_recep; Prog_receptor; zf-C4
Pfam	PF00104 PF02161 PF00105
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus
Biological Process	GO:0071371	cellular response to gonadotropin stimulus
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus
Biological Process	GO:0016101	diterpenoid metabolic process
Biological Process	GO:0002070	epithelial cell maturation
Biological Process	GO:0044849	estrous cycle
Biological Process	GO:0060180	female mating behavior
Biological Process	GO:0048286	lung alveolus development
Biological Process	GO:0001553	luteinization
Biological Process	GO:0030879	mammary gland development
Biological Process	GO:0043066	negative regulation of apoptotic process
Biological Process	GO:0010629	negative regulation of gene expression
Biological Process	GO:1904709	negative regulation of granulosa cell apoptotic process
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated
Biological Process	GO:0001542	ovulation from ovarian follicle
Biological Process	GO:0038001	paracrine signaling
Biological Process	GO:0008284	positive regulation of cell population proliferation
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0050847	progesterone receptor signaling pathway
Biological Process	GO:0050678	regulation of epithelial cell proliferation
Biological Process	GO:0006355	regulation of transcription, DNA-templated
Biological Process	GO:0042220	response to cocaine
Biological Process	GO:0043627	response to estrogen
Biological Process	GO:0032570	response to progesterone
Biological Process	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis
molecular function	GO:0051117	ATPase binding
molecular function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function	GO:0019899	enzyme binding
molecular function	GO:0042562	hormone binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0004879	nuclear receptor activity
molecular function	GO:0070491	repressing transcription factor binding
molecular function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function	GO:0043565	sequence-specific DNA binding
molecular function	GO:0005102	signaling receptor binding
molecular function	GO:0005496	steroid binding
molecular function	GO:0003707	steroid hormone receptor activity
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0030424	axon
cellular component	GO:0043679	axon terminus
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0030425	dendrite
cellular component	GO:0043197	dendritic spine
cellular component	GO:0005783	endoplasmic reticulum
cellular component	GO:0005739	mitochondrion
cellular component	GO:0043005	neuron projection
cellular component	GO:0005634	nucleus
cellular component	GO:0043204	perikaryon
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000130	Estradiol		272.38
BXGC0001325	Progesterone		314.46
BXGC0006362	Estrone		270.37
BXGC0020800	Testosterone		288.21

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}