Showing entry for BDNF/NT-3 growth factors receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016074
Protein NameBDNF/NT-3 growth factors receptor
Uniport IdQ63604
GeneNtrk2
Gene Id25054
DomainI-set; LRR_8; Pkinase_Tyr; TPKR_C2
Pfam PF07679   PF13855   PF07714   PF16920  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0031547 brain-derived neurotrophic factor receptor signaling pathway
Biological Process GO:0035584 calcium-mediated signaling using intracellular calcium source
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0021954 central nervous system neuron development
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0007623 circadian rhythm
Biological Process GO:0007631 feeding behavior
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0006954 inflammatory response
Biological Process GO:0007612 learning
Biological Process GO:0007616 long-term memory
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0042490 mechanoreceptor differentiation
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0022011 myelination in peripheral nervous system
Biological Process GO:1902430 negative regulation of amyloid-beta formation
Biological Process GO:2000811 negative regulation of anoikis
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0007399 nervous system development
Biological Process GO:0007528 neuromuscular junction development
Biological Process GO:0019227 neuronal action potential propagation
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0001764 neuron migration
Biological Process GO:0048709 oligodendrocyte differentiation
Biological Process GO:0048935 peripheral nervous system neuron development
Biological Process GO:0050772 positive regulation of axonogenesis
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:2000324 positive regulation of glucocorticoid receptor signaling pathway
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0050773 regulation of dendrite development
Biological Process GO:0043087 regulation of GTPase activity
Biological Process GO:0043408 regulation of MAPK cascade
Biological Process GO:0019222 regulation of metabolic process
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0051896 regulation of protein kinase B signaling
Biological Process GO:0010996 response to auditory stimulus
Biological Process GO:0009416 response to light stimulus
Biological Process GO:0060041 retina development in camera-type eye
Biological Process GO:0046548 retinal rod cell development
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission
Biological Process GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission
Biological Process GO:0001570 vasculogenesis
molecular function GO:0005524 ATP binding
molecular function GO:0060175 brain-derived neurotrophic factor-activated receptor activity
molecular function GO:0048403 brain-derived neurotrophic factor binding
molecular function GO:0043121 neurotrophin binding
molecular function GO:0005030 neurotrophin receptor activity
molecular function GO:0002020 protease binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0004675 transmembrane receptor protein serine/threonine kinase activity
molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity
cellular component GO:0030424 axon
cellular component GO:0043679 axon terminus
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0005769 early endosome
cellular component GO:0031901 early endosome membrane
cellular component GO:0005768 endosome
cellular component GO:0060076 excitatory synapse
cellular component GO:0000139 Golgi membrane
cellular component GO:0030426 growth cone
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043204 perikaryon
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0048786 presynaptic active zone
cellular component GO:0043235 receptor complex
cellular component GO:0005791 rough endoplasmic reticulum
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0021835 7,8-Dihydroxyflavone 254.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein