Showing entry for Adapter molecule crk


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016108
Protein NameAdapter molecule crk
Uniport IdQ64010
GeneCrk
Gene Id12928
DomainSH2; SH3_1; SH3_2
Pfam PF00017   PF00018   PF07653  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:1990859 cellular response to endothelin
Biological Process GO:1990314 cellular response to insulin-like growth factor stimulus
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0071732 cellular response to nitric oxide
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0098749 cerebellar neuron development
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0016358 dendrite development
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0030010 establishment of cell polarity
Biological Process GO:0035685 helper T cell diapedesis
Biological Process GO:0021766 hippocampus development
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:2000146 negative regulation of cell motility
Biological Process GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
Biological Process GO:0061045 negative regulation of wound healing
Biological Process GO:0001764 neuron migration
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0014911 positive regulation of smooth muscle cell migration
Biological Process GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Biological Process GO:0038026 reelin-mediated signaling pathway
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0033628 regulation of cell adhesion mediated by integrin
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0050773 regulation of dendrite development
Biological Process GO:0043087 regulation of GTPase activity
Biological Process GO:1902531 regulation of intracellular signal transduction
Biological Process GO:0002685 regulation of leukocyte migration
Biological Process GO:0043393 regulation of protein binding
Biological Process GO:0035020 regulation of Rac protein signal transduction
Biological Process GO:0009966 regulation of signal transduction
Biological Process GO:2000404 regulation of T cell migration
Biological Process GO:0061847 response to cholecystokinin
Biological Process GO:0035728 response to hepatocyte growth factor
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:1901652 response to peptide
Biological Process GO:0001878 response to yeast
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0019899 enzyme binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0005159 insulin-like growth factor receptor binding
molecular function GO:0001784 phosphotyrosine residue binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0030674 protein-macromolecule adaptor activity
molecular function GO:0045309 protein phosphorylated amino acid binding
molecular function GO:0043621 protein self-association
molecular function GO:1990782 protein tyrosine kinase binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0042169 SH2 domain binding
molecular function GO:0017124 SH3 domain binding
molecular function GO:0035591 signaling adaptor activity
molecular function GO:0030159 signaling receptor complex adaptor activity
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein