Showing entry for Bcl-2-like protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016115
Protein NameBcl-2-like protein 1
Uniport IdQ64373
GeneBcl2l1
Gene Id12048
DomainBcl-2; BH4
Pfam PF00452   PF02180  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071839 apoptotic process in bone marrow cell
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0071312 cellular response to alkaloid
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0071480 cellular response to gamma radiation
Biological Process GO:0051607 defense response to virus
Biological Process GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0009566 fertilization
Biological Process GO:0007281 germ cell development
Biological Process GO:0097284 hepatocyte apoptotic process
Biological Process GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0008584 male gonad development
Biological Process GO:0070584 mitochondrion morphogenesis
Biological Process GO:0007093 mitotic cell cycle checkpoint
Biological Process GO:2000811 negative regulation of anoikis
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Biological Process GO:1900118 negative regulation of execution phase of apoptosis
Biological Process GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
Biological Process GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1903077 negative regulation of protein localization to plasma membrane
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0001541 ovarian follicle development
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:2001171 positive regulation of ATP biosynthetic process
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:2000809 positive regulation of synaptic vesicle clustering
Biological Process GO:1900244 positive regulation of synaptic vesicle endocytosis
Biological Process GO:2000302 positive regulation of synaptic vesicle exocytosis
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0040008 regulation of growth
Biological Process GO:1900452 regulation of long-term synaptic depression
Biological Process GO:0046902 regulation of mitochondrial membrane permeability
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0001836 release of cytochrome c from mitochondria
Biological Process GO:0046898 response to cycloheximide
Biological Process GO:0034097 response to cytokine
Biological Process GO:0002931 response to ischemia
Biological Process GO:0009314 response to radiation
Biological Process GO:0009615 response to virus
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0019050 suppression by virus of host apoptotic process
Biological Process GO:0036466 synaptic vesicle recycling via endosome
molecular function GO:0051434 BH3 domain binding
molecular function GO:0051400 BH domain binding
molecular function GO:0030276 clathrin binding
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0051020 GTPase binding
molecular function GO:0042802 identical protein binding
molecular function GO:0097371 MDM2/MDM4 family protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0008134 transcription factor binding
cellular component GO:0097136 Bcl-2 family protein complex
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005740 mitochondrial envelope
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0031966 mitochondrial membrane
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0031965 nuclear membrane
cellular component GO:0098793 presynapse
cellular component GO:0030672 synaptic vesicle membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein