Showing entry for Glutamine-dependent NAD(+) synthetase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016324
Protein NameGlutamine-dependent NAD(+) synthetase
Uniport IdQ6IA69
GeneNADSYN1
Gene Id55191
DomainCN_hydrolase; NAD_synthase
Pfam PF00795   PF02540  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009435 NAD biosynthetic process
Biological Process GO:0019674 NAD metabolic process
molecular function GO:0005524 ATP binding
molecular function GO:0004359 glutaminase activity
molecular function GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196807 Nicotinate metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0035579 BXGD002560 Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0042870 BXGD003008 Vitamin D Deficiency Nutritional and Metabolic Diseases
C0262586 BXGD005258 Osteopenia/osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0426706 BXGD008574 Absent kidney
C0523979 BXGD009227 Vitamin D3 measurement
C0919758 BXGD011440 Vitamin D measurement
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0006162 L-Glutamic acid 147.13
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein