Showing entry for Ras-related protein Rab-12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016330
Protein NameRas-related protein Rab-12
Uniport IdQ6IQ22
GeneRAB12
Gene Id201475
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006914 autophagy
Biological Process GO:0044257 cellular protein catabolic process
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0008333 endosome to lysosome transport
Biological Process GO:0016239 positive regulation of macroautophagy
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0009306 protein secretion
Biological Process GO:0032482 Rab protein signal transduction
Biological Process GO:0017157 regulation of exocytosis
Biological Process GO:0006904 vesicle docking involved in exocytosis
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
cellular component GO:0005776 autophagosome
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0000139 Golgi membrane
cellular component GO:0032593 insulin-responsive compartment
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005764 lysosome
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein