Showing entry for 2',5'-phosphodiesterase 12



                       
General Target Information
BXGT IdBXGT016353
Protein Name2',5'-phosphodiesterase 12
Uniport IdQ6L8Q7
GenePDE12
Gene Id201626
DomainExo_endo_phos
Pfam PF03372  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071359 cellular response to dsRNA
Biological Process GO:0035457 cellular response to interferon-alpha
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0051607 defense response to virus
Biological Process GO:0000958 mitochondrial mRNA catabolic process
Biological Process GO:0006397 mRNA processing
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0090324 negative regulation of oxidative phosphorylation
Biological Process GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Biological Process GO:0090305 nucleic acid phosphodiester bond hydrolysis
Biological Process GO:0045070 positive regulation of viral genome replication
Biological Process GO:0044528 regulation of mitochondrial mRNA stability
Biological Process GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0004527 exonuclease activity
molecular function GO:0046872 metal ion binding
molecular function GO:0034611 oligoribonucleotidase activity
molecular function GO:0004535 poly(A)-specific ribonuclease activity
cellular component GO:0005829 cytosol
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-8983711 OAS antiviral response
R-HSA-913531 Interferon Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017636 BXGD001131 Glioblastoma Neoplasms
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0206617 BXGD004186 Cardiovirus Infections Infections
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein