Showing entry for Tyrosine-protein kinase Fgr


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016458
Protein NameTyrosine-protein kinase Fgr
Uniport IdQ6P6U0
GeneFgr
Gene Id79113
DomainPkinase_Tyr; SH2; SH3_1
Pfam PF07714   PF00017   PF00018  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030282 bone mineralization
Biological Process GO:0030154 cell differentiation
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0045087 innate immune response
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0032815 negative regulation of natural killer cell activation
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0043306 positive regulation of mast cell degranulation
Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0045088 regulation of innate immune response
Biological Process GO:0050764 regulation of phagocytosis
Biological Process GO:0045859 regulation of protein kinase activity
Biological Process GO:0048705 skeletal system morphogenesis
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0034988 Fc-gamma receptor I complex binding
molecular function GO:0034987 immunoglobulin receptor binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0001784 phosphotyrosine residue binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0016235 aggresome
cellular component GO:0005829 cytosol
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005758 mitochondrial intermembrane space
cellular component GO:0005886 plasma membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006193 Ellagic acid 302.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein