Showing entry for Serine/threonine-protein kinase ULK3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016467
Protein NameSerine/threonine-protein kinase ULK3
Uniport IdQ6PHR2
GeneULK3
Gene Id25989
DomainMIT; Pkinase
Pfam PF04212   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006914 autophagy
Biological Process GO:0090398 cellular senescence
Biological Process GO:0072537 fibroblast activation
Biological Process GO:0045879 negative regulation of smoothened signaling pathway
Biological Process GO:0045880 positive regulation of smoothened signaling pathway
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0007224 smoothened signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0097542 ciliary tip
cellular component GO:0005737 cytoplasm
cellular component GO:0000407 phagophore assembly site
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5632684 Hedgehog 'on' state
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein