Showing entry for Sortilin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016468
Protein NameSortilin
Uniport IdQ6PHU5
GeneSort1
Gene Id20661
DomainSortilin-Vps10; Sortilin_C
Pfam PF15902   PF15901  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006897 endocytosis
Biological Process GO:0008333 endosome to lysosome transport
Biological Process GO:0032509 endosome transport via multivesicular body sorting pathway
Biological Process GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:0046323 glucose import
Biological Process GO:0006895 Golgi to endosome transport
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0014902 myotube differentiation
Biological Process GO:0045599 negative regulation of fat cell differentiation
Biological Process GO:0051005 negative regulation of lipoprotein lipase activity
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0048011 neurotrophin TRK receptor signaling pathway
Biological Process GO:0001503 ossification
Biological Process GO:0048227 plasma membrane to endosome transport
Biological Process GO:1904037 positive regulation of epithelial cell apoptotic process
Biological Process GO:0006892 post-Golgi vesicle-mediated transport
Biological Process GO:0006622 protein targeting to lysosome
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0032868 response to insulin
Biological Process GO:0016050 vesicle organization
molecular function GO:0019899 enzyme binding
molecular function GO:0048406 nerve growth factor binding
molecular function GO:0010465 nerve growth factor receptor activity
molecular function GO:0030379 neurotensin receptor activity, non-G protein-coupled
molecular function GO:1905394 retromer complex binding
cellular component GO:0009986 cell surface
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0030136 clathrin-coated vesicle
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005769 early endosome
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0010008 endosome membrane
cellular component GO:0005794 Golgi apparatus
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005764 lysosome
cellular component GO:0043025 neuronal cell body
cellular component GO:0031965 nuclear membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0030140 trans-Golgi network transport vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein