protein

Showing entry for DNA replication ATP-dependent helicase/nuclease DNA2

General Target Information
BXGT Id	BXGT016633
Protein Name	DNA replication ATP-dependent helicase/nuclease DNA2
Uniport Id	Q6ZQJ5
Gene	Dna2
Gene Id	327762
Domain	A_11; A_12; Dna2
Pfam	PF13086 PF13087 PF08696
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006284	base-excision repair
Biological Process	GO:0000729	DNA double-strand break processing
Biological Process	GO:0006260	DNA replication
Biological Process	GO:0033567	DNA replication, Okazaki fragment processing
Biological Process	GO:0043137	DNA replication, removal of RNA primer
Biological Process	GO:0000076	DNA replication checkpoint
Biological Process	GO:0043504	mitochondrial DNA repair
Biological Process	GO:0006264	mitochondrial DNA replication
Biological Process	GO:1902990	mitotic telomere maintenance via semi-conservative replication
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis
Biological Process	GO:0045740	positive regulation of DNA replication
Biological Process	GO:0071932	replication fork reversal
Biological Process	GO:0000723	telomere maintenance
molecular function	GO:0051539	4 iron, 4 sulfur cluster binding
molecular function	GO:0043139	5'-3' DNA helicase activity
molecular function	GO:0017108	5'-flap endonuclease activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0003677	DNA binding
molecular function	GO:0003678	DNA helicase activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004518	nuclease activity
molecular function	GO:0003723	RNA binding
molecular function	GO:0017116	single-stranded DNA helicase activity
molecular function	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005760	gamma DNA polymerase complex
cellular component	GO:0042645	mitochondrial nucleoid
cellular component	GO:0005739	mitochondrion
cellular component	GO:0000784	nuclear chromosome, telomeric region
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}