Showing entry for Transient receptor potential cation channel subfamily V member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016657
Protein NameTransient receptor potential cation channel subfamily V member 1
Uniport IdQ704Y3
GeneTrpv1
Gene Id193034
DomainAnk_2; Ion_trans
Pfam PF12796   PF00520  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048266 behavioral response to pain
Biological Process GO:0098703 calcium ion import across plasma membrane
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0006812 cation transport
Biological Process GO:0071468 cellular response to acidic pH
Biological Process GO:0071312 cellular response to alkaloid
Biological Process GO:0071318 cellular response to ATP
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0034605 cellular response to heat
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0071502 cellular response to temperature stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0050968 detection of chemical stimulus involved in sensory perception of pain
Biological Process GO:0050965 detection of temperature stimulus involved in sensory perception of pain
Biological Process GO:0050960 detection of temperature stimulus involved in thermoception
Biological Process GO:0002024 diet induced thermogenesis
Biological Process GO:0001660 fever generation
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0090212 negative regulation of establishment of blood-brain barrier
Biological Process GO:0010459 negative regulation of heart rate
Biological Process GO:0010917 negative regulation of mitochondrial membrane potential
Biological Process GO:0003085 negative regulation of systemic arterial blood pressure
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0002790 peptide secretion
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0060454 positive regulation of gastric acid secretion
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:1901594 response to capsazepine
Biological Process GO:0009408 response to heat
Biological Process GO:0010243 response to organonitrogen compound
Biological Process GO:0048265 response to pain
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0009268 response to pH
Biological Process GO:0050954 sensory perception of mechanical stimulus
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0060083 smooth muscle contraction involved in micturition
Biological Process GO:0001659 temperature homeostasis
Biological Process GO:0014832 urinary bladder smooth muscle contraction
molecular function GO:0005524 ATP binding
molecular function GO:0005262 calcium channel activity
molecular function GO:0015278 calcium-release channel activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0005261 cation channel activity
molecular function GO:0008324 cation transmembrane transporter activity
molecular function GO:0017081 chloride channel regulator activity
molecular function GO:0005231 excitatory extracellular ligand-gated ion channel activity
molecular function GO:0005230 extracellular ligand-gated ion channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005216 ion channel activity
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0046872 metal ion binding
molecular function GO:0035091 phosphatidylinositol binding
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0097603 temperature-gated ion channel activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0032591 dendritic spine membrane
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031226 intrinsic component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0034035 Capsaicin 305.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein