Showing entry for Cytochrome b5 reductase 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016992
Protein NameCytochrome b5 reductase 4
Uniport IdQ7L1T6
GeneCYB5R4
Gene Id51167
DomainCS; Cyt-b5; FAD_binding_6; NAD_binding_1
Pfam PF04969   PF00173   PF00970   PF00175  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00520 Amino sugar and nucleotide sugar metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015701 bicarbonate transport
Biological Process GO:0048468 cell development
Biological Process GO:0003032 detection of oxygen
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0030073 insulin secretion
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0006801 superoxide metabolic process
molecular function GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H
molecular function GO:0020037 heme binding
molecular function GO:0046872 metal ion binding
molecular function GO:0016174 NAD(P)H oxidase (H(2)O(2)-forming activity
molecular function GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1237044 Erythrocytes take up carbon dioxide and release oxygen
R-HSA-1480926 O2/CO2 exchange in erythrocytes
R-HSA-382551 Transport of small molecules
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0008676 Haem 616.49
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein