Showing entry for RNA N6-adenosine-methyltransferase METTL16


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017623
Protein NameRNA N6-adenosine-methyltransferase METTL16
Uniport IdQ86W50
GeneMETTL16
Gene Id79066
DomainMethyltransf_10
Pfam PF05971  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006402 mRNA catabolic process
Biological Process GO:0061157 mRNA destabilization
Biological Process GO:0080009 mRNA methylation
Biological Process GO:1905869 negative regulation of 3'-UTR-mediated mRNA stabilization
Biological Process GO:0010608 posttranscriptional regulation of gene expression
Biological Process GO:0048024 regulation of mRNA splicing, via spliceosome
Biological Process GO:0070475 rRNA base methylation
Biological Process GO:0006556 S-adenosylmethionine biosynthetic process
Biological Process GO:0120049 snRNA (adenine-N6)-methylation
molecular function GO:0052907 23S rRNA (adenine(1618)-N(6))-methyltransferase activity
molecular function GO:0001734 mRNA (N6-adenosine)-methyltransferase activity
molecular function GO:0003723 RNA binding
molecular function GO:0035613 RNA stem-loop binding
molecular function GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity
molecular function GO:0030629 U6 snRNA 3'-end binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0020706 Dithioerythritol 154.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein