Showing entry for 4-hydroxy-2-oxoglutarate aldolase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017628
Protein Name4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Uniport IdQ86XE5
GeneHOGA1
Gene Id112817
DomainDHDPS
Pfam PF00701  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00330 Arginine and proline metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019470 4-hydroxyproline catabolic process
Biological Process GO:0009436 glyoxylate catabolic process
Biological Process GO:0046487 glyoxylate metabolic process
Biological Process GO:0033609 oxalate metabolic process
Biological Process GO:0042866 pyruvate biosynthetic process
molecular function GO:0008700 4-hydroxy-2-oxoglutarate aldolase activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-389661 Glyoxylate metabolism and glycine degradation
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0013428 BXGD000840 Dysuria Pathological Conditions, Signs and Symptoms
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020500 BXGD001408 Hyperoxaluria Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020501 BXGD001409 Primary Hyperoxaluria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027709 BXGD002026 Nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0042023 BXGD002948 Increased frequency of micturition Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0201874 BXGD004054 Amino acids measurement
C0202202 BXGD004082 Protein measurement
C0523465 BXGD009209 Serum albumin measurement
C1833683 BXGD013938 NEPHROLITHIASIS, CALCIUM OXALATE Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3150878 BXGD018345 Primary hyperoxaluria type III Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein