Showing entry for E3 ubiquitin-protein ligase NRDP1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017910
Protein NameE3 ubiquitin-protein ligase NRDP1
Uniport IdQ8BH75
GeneRnf41
Gene Id67588
DomainUSP8_interact; zf-C3HC4_2
Pfam PF08941  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006914 autophagy
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:1901525 negative regulation of mitophagy
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:2000379 positive regulation of reactive oxygen species metabolic process
Biological Process GO:0010498 proteasomal protein catabolic process
Biological Process GO:0051865 protein autoubiquitination
Biological Process GO:0000209 protein polyubiquitination
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:2000114 regulation of establishment of cell polarity
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0045619 regulation of lymphocyte differentiation
Biological Process GO:0043408 regulation of MAPK cascade
Biological Process GO:0045637 regulation of myeloid cell differentiation
Biological Process GO:0051896 regulation of protein kinase B signaling
Biological Process GO:2000377 regulation of reactive oxygen species metabolic process
molecular function GO:0005128 erythropoietin receptor binding
molecular function GO:0042802 identical protein binding
molecular function GO:0005135 interleukin-3 receptor binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0017160 Ral GTPase binding
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0061630 ubiquitin protein ligase activity
molecular function GO:0004842 ubiquitin-protein transferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0071782 endoplasmic reticulum tubular network
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein