Showing entry for DIS3-like exonuclease 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017940
Protein NameDIS3-like exonuclease 2
Uniport IdQ8CI75
GeneDis3l2
Gene Id208718
DomainDis3l2_C_term; OB_Dis3; RNB; Rrp44_CSD1
Pfam PF17877   PF17849   PF00773   PF17216  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0010587 miRNA catabolic process
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0051306 mitotic sister chromatid separation
Biological Process GO:0006402 mRNA catabolic process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic
Biological Process GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
Biological Process GO:1990074 polyuridylation-dependent mRNA catabolic process
Biological Process GO:0019827 stem cell population maintenance
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0008266 poly(U) RNA binding
molecular function GO:0004540 ribonuclease activity
cellular component GO:0005737 cytoplasm
cellular component GO:0000178 exosome (RNase complex)
cellular component GO:0000932 P-body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein