Showing entry for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017942
Protein Name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Uniport IdQ8CIH5
GenePlcg2
Gene Id234779
DomainC2; PI-PLC-X; PI-PLC-Y; SH2; SH3_1
Pfam PF00168   PF00388   PF00387   PF00017   PF00018  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032237 activation of store-operated calcium channel activity
Biological Process GO:0030183 B cell differentiation
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0002316 follicular B cell differentiation
Biological Process GO:0032959 inositol trisphosphate biosynthetic process
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0043069 negative regulation of programmed cell death
Biological Process GO:0006661 phosphatidylinositol biosynthetic process
Biological Process GO:0009395 phospholipid catabolic process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0010634 positive regulation of epithelial cell migration
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:0032481 positive regulation of type I interferon production
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0033198 response to ATP
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0032026 response to magnesium ion
Biological Process GO:0050852 T cell receptor signaling pathway
molecular function GO:0004435 phosphatidylinositol phospholipase C activity
molecular function GO:0004629 phospholipase C activity
molecular function GO:0140031 phosphorylation-dependent protein binding
molecular function GO:0001784 phosphotyrosine residue binding
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0036869 Harpagoside 494.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein