protein

Showing entry for DNA dC->dU-editing enzyme APOBEC-3F

General Target Information
BXGT Id	BXGT018337
Protein Name	DNA dC->dU-editing enzyme APOBEC-3F
Uniport Id	Q8IUX4
Gene	APOBEC3F
Gene Id	200316
Domain	APOBEC_N; NAD2
Pfam	-
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
6. Human Diseases	6.9 Infectious diseases: Viral	hsa05170	Human immunodeficiency virus 1 infection

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0016553	base conversion or substitution editing
Biological Process	GO:0016554	cytidine to uridine editing
Biological Process	GO:0051607	defense response to virus
Biological Process	GO:0070383	DNA cytosine deamination
Biological Process	GO:0080111	DNA demethylation
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process	GO:0010529	negative regulation of transposition
Biological Process	GO:0045071	negative regulation of viral genome replication
Biological Process	GO:0048525	negative regulation of viral process
Biological Process	GO:0002230	positive regulation of defense response to virus by host
molecular function	GO:0004126	cytidine deaminase activity
molecular function	GO:0047844	deoxycytidine deaminase activity
molecular function	GO:0042802	identical protein binding
molecular function	GO:0003723	RNA binding
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0030895	apolipoprotein B mRNA editing enzyme complex
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005634	nucleus
cellular component	GO:0000932	P-body
cellular component	GO:1990904	ribonucleoprotein complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0019163	BXGD001295	Hepatitis B	Digestive System Diseases; Infections
C0019693	BXGD001346	HIV Infections	Infections; Immune System Diseases
C0021051	BXGD001475	Immunologic Deficiency Syndromes	Immune System Diseases
C0424605	BXGD008535	Developmental delay (disorder)	Mental Disorders
C0557874	BXGD009444	Global developmental delay
C1141957	BXGD011726	HIV disease progression
C1535939	BXGD013323	Pneumocystis jiroveci pneumonia	Infections; Respiratory Tract Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2363741	BXGD017100	HIV-1 infection
C3714514	BXGD019409	Infection	Infections
C3826758	BXGD019733	AIDS (Disease)
C3854222	BXGD019826	Human immunodeficiency virus (HIV) II infection category B1

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000805	Bis(2-furanylmethyl) disulfide		226.32
BXGC0000952	6-Oxocamphor		457.91
BXGC0001691	Questiomycin A		212.2
BXGC0001823	Morusinol		438.47
BXGC0002906	Caffeic acid ester		284.31
BXGC0003696	Quercetin 3-O-methyl-ether		316.26
BXGC0005043	1-Hydroxy-10-methylacridone		225.24
BXGC0005319	Garcinone E		464.55
BXGC0005721	Bisdemethoxycurcumin		308.33
BXGC0005982	Curcumin		368.38
BXGC0006107	alpha-Linolenic acid		278.43
BXGC0007028	beta-Thujaplicin		164.2
BXGC0008365	Colubrinic acid		470.68
BXGC0012377	Nagilactone B		364.15
BXGC0015106	[(3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-Dihydroxy-10,13-Dimethyl-17-(5-Oxo-2H-Furan-3-Yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-Tetradecahydrocyclopenta[A]Phenanthren-16-Yl] Acetate		432.25
BXGC0017933	Sulfuretin		270.05
BXGC0020737	Protoapigenone		286.05
BXGC0024641	Methyl (1R)-1-Hydroxy-7-(Hydroxymethyl)-1,4A,5,7A-Tetrahydrocyclopenta[C]Pyran-4-Carboxylate		226.08
BXGC0024813	Demethoxycurcumin		338.12
BXGC0025394	Scoulerine		327.15
BXGC0026607	epiberberine		336.12
BXGC0026943	Toxyloxanthone C		328.09
BXGC0028778	Fangchinoline		608.29
BXGC0030010	Michler's Ketone		268.16
BXGC0031326	Paxilline		435.24
BXGC0035226	Betulinic Acid		456.36
BXGC0036864	Cyclovalone		366.15
BXGC0038066	Rescinnamine		634.29
BXGC0039520	[(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] (E)-2-Methylbut-2-Enoate		360.16
BXGC0040936	Sid26657808		284.07
BXGC0041609	Grossheimin		262.12
BXGC0042035	raubasine		352.18
BXGC0042110	4-(4-DIMETHYLAMINOSTYRYL)QUINOLINE		274.15
BXGC0046862	Benzo[Def]Chrysene		252.09
BXGC0049858	Chalcone		208.09
BXGC0051013	N-Phenylnaphthalen-1-Amine		219.1
BXGC0051864	Aristolochic Acid		341.05
BXGC0052374	Reserpine		608.27

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}