Showing entry for Mitochondrial Rho GTPase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018361
Protein NameMitochondrial Rho GTPase 1
Uniport IdQ8IXI2
GeneRHOT1
Gene Id55288
DomainEF_assoc_1; EF_assoc_2; Ras
Pfam PF08355   PF08356   PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019725 cellular homeostasis
Biological Process GO:0034640 establishment of mitochondrion localization by microtubule attachment
Biological Process GO:0097345 mitochondrial outer membrane permeabilization
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0047497 mitochondrion transport along microtubule
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0010821 regulation of mitochondrion organization
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:1902513 regulation of organelle transport along microtubule
Biological Process GO:0051056 regulation of small GTPase mediated signal transduction
molecular function GO:0005509 calcium ion binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
cellular component GO:0005829 cytosol
cellular component GO:0031307 integral component of mitochondrial outer membrane
cellular component GO:0016020 membrane
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194840 Rho GTPase cycle
R-HSA-392499 Metabolism of proteins
R-HSA-5688426 Deubiquitination
R-HSA-5689880 Ub-specific processing proteases
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0238478 BXGD004940 Transient erythroblastopenia of childhood Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein