Showing entry for Glycerol-3-phosphate dehydrogenase 1-like protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018502
Protein NameGlycerol-3-phosphate dehydrogenase 1-like protein
Uniport IdQ8N335
GeneGPD1L
Gene Id23171
DomainNAD_Gly3P_dh_C; NAD_Gly3P_dh_N
Pfam PF07479   PF01210  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0046168 glycerol-3-phosphate catabolic process
Biological Process GO:0006734 NADH metabolic process
Biological Process GO:0019674 NAD metabolic process
Biological Process GO:0033137 negative regulation of peptidyl-serine phosphorylation
Biological Process GO:0090038 negative regulation of protein kinase C signaling
Biological Process GO:0006654 phosphatidic acid biosynthetic process
Biological Process GO:2000010 positive regulation of protein localization to cell surface
Biological Process GO:0010765 positive regulation of sodium ion transport
Biological Process GO:0002027 regulation of heart rate
Biological Process GO:2000649 regulation of sodium ion transmembrane transporter activity
Biological Process GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
Biological Process GO:0086005 ventricular cardiac muscle cell action potential
molecular function GO:0044325 ion channel binding
molecular function GO:0051287 NAD binding
molecular function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0017080 sodium channel regulator activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0009331 glycerol-3-phosphate dehydrogenase complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483166 Synthesis of PA
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030591 BXGD002247 Paroxysmal ventricular tachycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0037052 BXGD002662 Sick Sinus Syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0038644 BXGD002776 Sudden infant death syndrome Pathological Conditions, Signs and Symptoms
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039240 BXGD002804 Supraventricular tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085614 BXGD003205 First degree atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085615 BXGD003206 Right bundle branch block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155707 BXGD003813 Trifascicular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0264893 BXGD005433 Nodal rhythm disorder Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0348626 BXGD007878 Other specified cardiac arrhythmias Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0428908 BXGD008641 Sinus Node Dysfunction (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0520886 BXGD009118 ST segment elevation (finding) Cardiovascular Diseases
C0600125 BXGD009694 Prolonged PR interval Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1142166 BXGD011736 Brugada Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1399226 BXGD013003 Ectopic rhythm Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1611743 BXGD013456 Familial (FPAH)
C1858430 BXGD015792 Death in infancy
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2673193 BXGD017187 Brugada Syndrome 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2748542 BXGD017596 CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C3715208 BXGD019451 AV Block First Degree by ECG Finding Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4551804 BXGD023411 Brugada Syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein