Showing entry for MAGUK p55 subfamily member 5



                       
General Target Information
BXGT IdBXGT018507
Protein NameMAGUK p55 subfamily member 5
Uniport IdQ8N3R9
GeneMPP5
Gene Id64398
DomainGuanylate_kin; L27; L27_N; PDZ; SH3_2
Pfam PF00625   PF02828   PF09060   PF00595   PF07653  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070830 bicellular tight junction assembly
Biological Process GO:0090162 establishment of epithelial cell polarity
Biological Process GO:0002011 morphogenesis of an epithelial sheet
Biological Process GO:0032288 myelin assembly
Biological Process GO:0032287 peripheral nervous system myelin maintenance
Biological Process GO:0035750 protein localization to myelin sheath abaxonal region
Biological Process GO:0072659 protein localization to plasma membrane
molecular function GO:0005524 ATP binding
molecular function GO:0019904 protein domain specific binding
cellular component GO:0005912 adherens junction
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
cellular component GO:0070062 extracellular exosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0043219 lateral loop
cellular component GO:0035749 myelin sheath adaxonal region
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0043220 Schmidt-Lanterman incisure
Reactome
Pathway Id Pathway Name
R-HSA-1500931 Cell-Cell communication
R-HSA-420029 Tight junction interactions
R-HSA-421270 Cell-cell junction organization
R-HSA-446728 Cell junction organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0042798 BXGD003003 Low Vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0339527 BXGD007260 Leber Congenital Amaurosis Eye Diseases
C0750974 BXGD010270 Brain Tumor, Primary Neoplasms; Nervous System Diseases
C2931258 BXGD017991 Amaurosis congenita of Leber, type 1 Eye Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein