Showing entry for Prostaglandin reductase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018529
Protein NameProstaglandin reductase 2
Uniport IdQ8N8N7
GenePTGR2
Gene Id145482
DomainADH_N_2; ADH_zinc_N
Pfam PF16884   PF00107  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006693 prostaglandin metabolic process
molecular function GO:0036132 13-prostaglandin reductase activity
molecular function GO:0047522 15-oxoprostaglandin 13-oxidase activity
cellular component GO:0005737 cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-2142753 Arachidonic acid metabolism
R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
R-HSA-556833 Metabolism of lipids
R-HSA-8978868 Fatty acid metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000647 L-Malic acid 134.09
BXGC0003705 Chloride 35.45
BXGC0006125 Nicotinamide 122.12
BXGC0011627 Glycyrrhetic acid 470.69
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein