Showing entry for Inositol polyphosphate multikinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018564
Protein NameInositol polyphosphate multikinase
Uniport IdQ8NFU5
GeneIPMK
Gene Id253430
DomainIPK
Pfam PF03770  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00562 Inositol phosphate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04070 Phosphatidylinositol signaling system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032958 inositol phosphate biosynthetic process
Biological Process GO:0043647 inositol phosphate metabolic process
Biological Process GO:0032957 inositol trisphosphate metabolic process
Biological Process GO:0070266 necroptotic process
molecular function GO:0005524 ATP binding
molecular function GO:0097243 flavonoid binding
molecular function GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity
molecular function GO:0000823 inositol-1,4,5-trisphosphate 6-kinase activity
molecular function GO:0000824 inositol tetrakisphosphate 3-kinase activity
molecular function GO:0047326 inositol tetrakisphosphate 5-kinase activity
molecular function GO:0000825 inositol tetrakisphosphate 6-kinase activity
molecular function GO:0051765 inositol tetrakisphosphate kinase activity
molecular function GO:0016301 kinase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0102732 myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity
molecular function GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity
molecular function GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483249 Inositol phosphate metabolism
R-HSA-1855191 Synthesis of IPs in the nucleus
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000314 Isorhamnetin 316.26
BXGC0000340 Kaempferol 286.24
BXGC0000516 Diosmetin 300.26
BXGC0002094 Rhamnetin 316.26
BXGC0002588 Magnesium 24.31
BXGC0005683 Quercetin 302.24
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein