Showing entry for Phosphoethanolamine/phosphocholine phosphatase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018800
Protein NamePhosphoethanolamine/phosphocholine phosphatase
Uniport IdQ8TCT1
GenePHOSPHO1
Gene Id162466
DomainPut_Phosphatase
Pfam PF06888  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035630 bone mineralization involved in bone maturation
Biological Process GO:0001958 endochondral ossification
Biological Process GO:0006656 phosphatidylcholine biosynthetic process
Biological Process GO:0006646 phosphatidylethanolamine biosynthetic process
Biological Process GO:0030500 regulation of bone mineralization
molecular function GO:0046872 metal ion binding
molecular function GO:0016791 phosphatase activity
molecular function GO:0052731 phosphocholine phosphatase activity
molecular function GO:0052732 phosphoethanolamine phosphatase activity
molecular function GO:0016462 pyrophosphatase activity
cellular component GO:0005829 cytosol
cellular component GO:0031012 extracellular matrix
cellular component GO:0065010 extracellular membrane-bounded organelle
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483191 Synthesis of PC
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483213 Synthesis of PE
R-HSA-1483257 Phospholipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005944 BXGD000355 Metabolic Bone Disorder Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0029442 BXGD002151 Osteomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Endocrine System Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0376154 BXGD007980 Skin callus Skin and Connective Tissue Diseases
C1855340 BXGD015490 Bowing of the long bones
C3887650 BXGD019911 Adult Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000409 Choline 104.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein