Showing entry for Pantothenate kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018818
Protein NamePantothenate kinase 1
Uniport IdQ8TE04
GenePANK1
Gene Id53354
DomainFumble
Pfam PF03630  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00770 Pantothenate and CoA biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015937 coenzyme A biosynthetic process
molecular function GO:1905502 acetyl-CoA binding
molecular function GO:0005524 ATP binding
molecular function GO:0004594 pantothenate kinase activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0071944 cell periphery
cellular component GO:0030118 clathrin coat
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0055037 recycling endosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196783 Coenzyme A biosynthesis
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-199220 Vitamin B5 (pantothenate) metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0018522 BXGD001198 Hallermann's Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0018523 BXGD001199 Hallervorden-Spatz Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0038160 BXGD002734 Staphylococcal Infections Infections
C0202098 BXGD004070 Insulin measurement
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0270724 BXGD006092 Infantile Neuroaxonal Dystrophy Nervous System Diseases
C0337438 BXGD007159 Glucose measurement
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0346648 BXGD007833 Malignant tumor of exocrine pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0393593 BXGD008103 Dystonia Disorders Nervous System Diseases
C0495706 BXGD009038 elevated blood glucose level
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0596887 BXGD009648 mathematical ability
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1611743 BXGD013456 Familial (FPAH)
C1837657 BXGD014256 Spondyloepiphyseal dysplasia, Omani type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1853578 BXGD015346 Neuroferritinopathy Nutritional and Metabolic Diseases; Nervous System Diseases
C1858479 BXGD015798 Spastic paraplegia 11, autosomal recessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2931356 BXGD018007 Spastic paraplegia type 5A, recessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2931845 BXGD018076 Neurodegeneration with brain iron accumulation (NBIA) Nutritional and Metabolic Diseases; Nervous System Diseases
C3550973 BXGD019143 NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002692 Arsenic 77.95
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein