Showing entry for E3 ubiquitin-protein ligase UHRF1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018917
Protein NameE3 ubiquitin-protein ligase UHRF1
Uniport IdQ8VDF2
GeneUhrf1
Gene Id18140
DomainPHD; SAD_SRA; TTD; ubiquitin
Pfam PF00628   PF02182   PF12148   PF00240  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:0006281 DNA repair
Biological Process GO:0010390 histone monoubiquitination
Biological Process GO:0016574 histone ubiquitination
Biological Process GO:0010216 maintenance of DNA methylation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0032270 positive regulation of cellular protein metabolic process
Biological Process GO:0051865 protein autoubiquitination
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0050678 regulation of epithelial cell proliferation
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0000987 cis-regulatory region sequence-specific DNA binding
molecular function GO:0044729 hemi-methylated DNA-binding
molecular function GO:0042393 histone binding
molecular function GO:0042802 identical protein binding
molecular function GO:0035064 methylated histone binding
molecular function GO:0008327 methyl-CpG binding
molecular function GO:0031493 nucleosomal histone binding
molecular function GO:0061630 ubiquitin protein ligase activity
molecular function GO:0004842 ubiquitin-protein transferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0000791 euchromatin
cellular component GO:0000792 heterochromatin
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005720 nuclear heterochromatin
cellular component GO:0016363 nuclear matrix
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0005657 replication fork
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein