protein

Showing entry for Hepatitis A virus cellular receptor 2 homolog

General Target Information
BXGT Id	BXGT018933
Protein Name	Hepatitis A virus cellular receptor 2 homolog
Uniport Id	Q8VIM0
Gene	Havcr2
Gene Id	171285
Domain	V-set
Pfam	PF07686
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0002250	adaptive immune response
Biological Process	GO:0071222	cellular response to lipopolysaccharide
Biological Process	GO:0050830	defense response to Gram-positive bacterium
Biological Process	GO:0006954	inflammatory response
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0002281	macrophage activation involved in immune response
Biological Process	GO:0060135	maternal process involved in female pregnancy
Biological Process	GO:0002519	natural killer cell tolerance induction
Biological Process	GO:1900425	negative regulation of defense response to bacterium
Biological Process	GO:0010629	negative regulation of gene expression
Biological Process	GO:0071656	negative regulation of granulocyte colony-stimulating factor production
Biological Process	GO:0002838	negative regulation of immune response to tumor cell
Biological Process	GO:2000521	negative regulation of immunological synapse formation
Biological Process	GO:0045824	negative regulation of innate immune response
Biological Process	GO:0032687	negative regulation of interferon-alpha production
Biological Process	GO:0032689	negative regulation of interferon-gamma production
Biological Process	GO:0032703	negative regulation of interleukin-2 production
Biological Process	GO:0032712	negative regulation of interleukin-3 production
Biological Process	GO:0032715	negative regulation of interleukin-6 production
Biological Process	GO:0030886	negative regulation of myeloid dendritic cell activation
Biological Process	GO:0032815	negative regulation of natural killer cell activation
Biological Process	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity
Biological Process	GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Biological Process	GO:0042130	negative regulation of T cell proliferation
Biological Process	GO:0002826	negative regulation of T-helper 1 type immune response
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production
Biological Process	GO:0032480	negative regulation of type I interferon production
Biological Process	GO:0032722	positive regulation of chemokine production
Biological Process	GO:0001819	positive regulation of cytokine production
Biological Process	GO:1900426	positive regulation of defense response to bacterium
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade
Biological Process	GO:0045089	positive regulation of innate immune response
Biological Process	GO:0032729	positive regulation of interferon-gamma production
Biological Process	GO:0032732	positive regulation of interleukin-1 production
Biological Process	GO:0032753	positive regulation of interleukin-4 production
Biological Process	GO:0043032	positive regulation of macrophage activation
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling
Biological Process	GO:0042102	positive regulation of T cell proliferation
Biological Process	GO:1904469	positive regulation of tumor necrosis factor secretion
Biological Process	GO:0002652	regulation of tolerance induction dependent upon immune response
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway
Biological Process	GO:0034154	toll-like receptor 7 signaling pathway
Biological Process	GO:0034162	toll-like receptor 9 signaling pathway
molecular function	GO:0046872	metal ion binding
cellular component	GO:0030054	cell junction
cellular component	GO:0009986	cell surface
cellular component	GO:0005769	early endosome
cellular component	GO:0005576	extracellular region
cellular component	GO:0001772	immunological synapse
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}