Showing entry for Cytosolic arginine sensor for mTORC1 subunit 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018988
Protein NameCytosolic arginine sensor for mTORC1 subunit 1
Uniport IdQ8WTX7
GeneCASTOR1
Gene Id652968
DomainACT_7; Castor1_N
Pfam PF13840   PF18700  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1903577 cellular response to L-arginine
Biological Process GO:1904262 negative regulation of TORC1 signaling
Biological Process GO:1902531 regulation of intracellular signal transduction
molecular function GO:0034618 arginine binding
molecular function GO:0042802 identical protein binding
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-2262752 Cellular responses to stress
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9639288 Amino acids regulate mTORC1
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0049200 Arginine 175.12
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein