Showing entry for Sialidase-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019004
Protein NameSialidase-4
Uniport IdQ8WWR8
GeneNEU4
Gene Id129807
DomainBNR_2
Pfam PF13088  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00511 Other glycan degradation
1. Metabolism 1.3 Lipid metabolism hsa00600 Sphingolipid metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006689 ganglioside catabolic process
Biological Process GO:0006516 glycoprotein catabolic process
Biological Process GO:0006687 glycosphingolipid metabolic process
Biological Process GO:0009313 oligosaccharide catabolic process
molecular function GO:0052794 exo-alpha-(2->3)-sialidase activity
molecular function GO:0052795 exo-alpha-(2->6)-sialidase activity
molecular function GO:0052796 exo-alpha-(2->8)-sialidase activity
molecular function GO:0004308 exo-alpha-sialidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0043202 lysosomal lumen
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0019866 organelle inner membrane
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-4085001 Sialic acid metabolism
R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-446219 Synthesis of substrates in N-glycan biosythesis
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0044778 Oseltamivir 312.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein