Showing entry for Three-prime repair exonuclease 1



                       
General Target Information
BXGT IdBXGT019306
Protein NameThree-prime repair exonuclease 1
Uniport IdQ91XB0
GeneTrex1
Gene Id22040
Domain-
Pfam -  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002253 activation of immune response
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0043277 apoptotic cell clearance
Biological Process GO:0003228 atrial cardiac muscle tissue development
Biological Process GO:0001568 blood vessel development
Biological Process GO:0035781 CD86 biosynthetic process
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0071480 cellular response to gamma radiation
Biological Process GO:0072711 cellular response to hydroxyurea
Biological Process GO:0035458 cellular response to interferon-beta
Biological Process GO:0071310 cellular response to organic substance
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0071357 cellular response to type I interferon
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0051607 defense response to virus
Biological Process GO:0072421 detection of DNA damage stimulus involved in DNA damage checkpoint
Biological Process GO:0072394 detection of stimulus involved in cell cycle checkpoint
Biological Process GO:0008340 determination of adult lifespan
Biological Process GO:0006308 DNA catabolic process
Biological Process GO:0032508 DNA duplex unwinding
Biological Process GO:0006259 DNA metabolic process
Biological Process GO:0006304 DNA modification
Biological Process GO:0006260 DNA replication
Biological Process GO:1904161 DNA synthesis involved in UV-damage excision repair
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0003007 heart morphogenesis
Biological Process GO:0003015 heart process
Biological Process GO:0097281 immune complex formation
Biological Process GO:0006955 immune response
Biological Process GO:0002383 immune response in brain or nervous system
Biological Process GO:0002379 immunoglobulin biosynthetic process involved in immune response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0002437 inflammatory response to antigenic stimulus
Biological Process GO:0045087 innate immune response
Biological Process GO:0032607 interferon-alpha production
Biological Process GO:0001822 kidney development
Biological Process GO:0002320 lymphoid progenitor cell differentiation
Biological Process GO:0002281 macrophage activation involved in immune response
Biological Process GO:0060339 negative regulation of type I interferon-mediated signaling pathway
Biological Process GO:0002251 organ or tissue specific immune response
Biological Process GO:0050821 protein stabilization
Biological Process GO:0050790 regulation of catalytic activity
Biological Process GO:0031323 regulation of cellular metabolic process
Biological Process GO:0043457 regulation of cellular respiration
Biological Process GO:0019217 regulation of fatty acid metabolic process
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0006110 regulation of glycolytic process
Biological Process GO:0002637 regulation of immunoglobulin production
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0045088 regulation of innate immune response
Biological Process GO:0046890 regulation of lipid biosynthetic process
Biological Process GO:1905671 regulation of lysosome organization
Biological Process GO:0061635 regulation of protein complex stability
Biological Process GO:0050863 regulation of T cell activation
Biological Process GO:0032680 regulation of tumor necrosis factor production
Biological Process GO:0032479 regulation of type I interferon production
Biological Process GO:0009411 response to UV
Biological Process GO:0072422 signal transduction involved in DNA damage checkpoint
Biological Process GO:0002457 T cell antigen processing and presentation
Biological Process GO:0032197 transposition, RNA-mediated
Biological Process GO:0060337 type I interferon signaling pathway
molecular function GO:0008296 3'-5'-exodeoxyribonuclease activity
molecular function GO:0008408 3'-5' exonuclease activity
molecular function GO:0032558 adenyl deoxyribonucleotide binding
molecular function GO:0003677 DNA binding
molecular function GO:0008301 DNA binding, bending
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0008853 exodeoxyribonuclease III activity
molecular function GO:0042802 identical protein binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0032405 MutLalpha complex binding
molecular function GO:0032407 MutSalpha complex binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0003697 single-stranded DNA binding
molecular function GO:0050699 WW domain binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0043596 nuclear replication fork
cellular component GO:0005634 nucleus
cellular component GO:0008250 oligosaccharyltransferase complex
cellular component GO:0032993 protein-DNA complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein