Showing entry for Mitogen-activated protein kinase 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019324
Protein NameMitogen-activated protein kinase 8
Uniport IdQ91Y86
GeneMapk8
Gene Id26419
DomainPkinase
Pfam PF00069  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071732 cellular response to nitric oxide
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0048263 determination of dorsal identity
Biological Process GO:0006954 inflammatory response
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0007254 JNK cascade
Biological Process GO:0007258 JUN phosphorylation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0097150 neuronal stem cell population maintenance
Biological Process GO:0001764 neuron migration
Biological Process GO:0031175 neuron projection development
Biological Process GO:0001503 ossification
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Biological Process GO:0010666 positive regulation of cardiac muscle cell apoptotic process
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0031281 positive regulation of cyclase activity
Biological Process GO:0090045 positive regulation of deacetylase activity
Biological Process GO:2000017 positive regulation of determination of dorsal identity
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0034352 positive regulation of glial cell apoptotic process
Biological Process GO:0031116 positive regulation of microtubule polymerization
Biological Process GO:0002052 positive regulation of neuroblast proliferation
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:2001224 positive regulation of neuron migration
Biological Process GO:0071803 positive regulation of podosome assembly
Biological Process GO:0051247 positive regulation of protein metabolic process
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:1901485 positive regulation of transcription factor catabolic process
Biological Process GO:0097300 programmed necrotic cell death
Biological Process GO:0061833 protein localization to tricellular tight junction
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0046605 regulation of centrosome cycle
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:1904809 regulation of dense core granule transport
Biological Process GO:1902595 regulation of DNA replication origin binding
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0045664 regulation of neuron differentiation
Biological Process GO:0032880 regulation of protein localization
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0046686 response to cadmium ion
Biological Process GO:0009408 response to heat
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0006970 response to osmotic stress
Biological Process GO:0009411 response to UV
Biological Process GO:0048511 rhythmic process
Biological Process GO:0007165 signal transduction
Biological Process GO:0051403 stress-activated MAPK cascade
Biological Process GO:0097050 type B pancreatic cell apoptotic process
molecular function GO:0005524 ATP binding
molecular function GO:0019899 enzyme binding
molecular function GO:0042826 histone deacetylase binding
molecular function GO:0035033 histone deacetylase regulator activity
molecular function GO:0004705 JUN kinase activity
molecular function GO:0016301 kinase activity
molecular function GO:0019894 kinesin binding
molecular function GO:0004707 MAP kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0030424 axon
cellular component GO:0097441 basal dendrite
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0032839 dendrite cytoplasm
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0002102 podosome
cellular component GO:0045202 synapse
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002094 Rhamnetin 316.26
BXGC0044857 Sp-600125 220.06
BXGC0045321 handelin 552.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein