protein

General Target Information
BXGT Id	BXGT019365
Protein Name	Rho-related GTP-binding protein Rho6
Uniport Id	Q92730
Gene	RND1
Gene Id	27289
Domain	Ras
Pfam	PF00071
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
5. Organismal Systems	5.8 Development	hsa04360	Axon guidance

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0030036	actin cytoskeleton organization
Biological Process	GO:0007015	actin filament organization
Biological Process	GO:0016477	cell migration
Biological Process	GO:0030865	cortical cytoskeleton organization
Biological Process	GO:0007162	negative regulation of cell adhesion
Biological Process	GO:0016322	neuron remodeling
Biological Process	GO:0032956	regulation of actin cytoskeleton organization
Biological Process	GO:0008360	regulation of cell shape
Biological Process	GO:0007264	small GTPase mediated signal transduction
molecular function	GO:0003924	GTPase activity
molecular function	GO:0005525	GTP binding
molecular function	GO:0019901	protein kinase binding
molecular function	GO:0005102	signaling receptor binding
cellular component	GO:0015629	actin cytoskeleton
cellular component	GO:0005912	adherens junction
cellular component	GO:0005938	cell cortex
cellular component	GO:0042995	cell projection
cellular component	GO:0005737	cytoplasm
cellular component	GO:0031410	cytoplasmic vesicle
cellular component	GO:0005856	cytoskeleton
cellular component	GO:0005829	cytosol
cellular component	GO:0043231	intracellular membrane-bounded organelle
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-1266738	Developmental Biology
R-HSA-1266738	Developmental Biology
R-HSA-373755	Semaphorin interactions
R-HSA-373755	Semaphorin interactions
R-HSA-399955	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
R-HSA-400685	Sema4D in semaphorin signaling
R-HSA-416550	Sema4D mediated inhibition of cell attachment and migration
R-HSA-416572	Sema4D induced cell migration and growth-cone collapse
R-HSA-422475	Axon guidance
R-HSA-422475	Axon guidance
R-HSA-9675108	Nervous system development
R-HSA-9675108	Nervous system development

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0017636	BXGD001131	Glioblastoma	Neoplasms
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0278878	BXGD006609	Adult Glioblastoma	Neoplasms
C0280474	BXGD006748	Childhood Glioblastoma	Neoplasms
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C1269955	BXGD012005	Tumor Cell Invasion
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1458155	BXGD013136	Mammary Neoplasms	Neoplasms; Skin and Connective Tissue Diseases
C1512981	BXGD013196	Mammary Tumorigenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C3539878	BXGD019087	Triple Negative Breast Neoplasms	Neoplasms; Skin and Connective Tissue Diseases
C4722518	BXGD023806	Triple-Negative Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases

Target protein-related compounds

Compounds

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}