Showing entry for Phosphomannomutase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019387
Protein NamePhosphomannomutase 1
Uniport IdQ92871
GenePMM1
Gene Id5372
DomainPMM
Pfam PF03332  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00051 Fructose and mannose metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00520 Amino sugar and nucleotide sugar metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0009298 GDP-mannose biosynthetic process
Biological Process GO:0006013 mannose metabolic process
Biological Process GO:0006487 protein N-linked glycosylation
Biological Process GO:0045047 protein targeting to ER
molecular function GO:0046872 metal ion binding
molecular function GO:0004615 phosphomannomutase activity
cellular component GO:0005829 cytosol
cellular component GO:0043025 neuronal cell body
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-446205 Synthesis of GDP-mannose
R-HSA-446219 Synthesis of substrates in N-glycan biosythesis
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0019189 BXGD001298 Hepatitis, Chronic Digestive System Diseases
C0027612 BXGD002003 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0349653 BXGD007946 Congenital disorder of glycosylation type 1A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein