Showing entry for Kallikrein-6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019388
Protein NameKallikrein-6
Uniport IdQ92876
GeneKLK6
Gene Id5653
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042982 amyloid precursor protein metabolic process
Biological Process GO:0007417 central nervous system development
Biological Process GO:0030574 collagen catabolic process
Biological Process GO:0042445 hormone metabolic process
Biological Process GO:0042552 myelination
Biological Process GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
Biological Process GO:0016540 protein autoprocessing
Biological Process GO:0045595 regulation of cell differentiation
Biological Process GO:0010975 regulation of neuron projection development
Biological Process GO:0009611 response to wounding
Biological Process GO:0042246 tissue regeneration
molecular function GO:0004252 serine-type endopeptidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005739 mitochondrion
cellular component GO:0005730 nucleolus
cellular component GO:0030141 secretory granule
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007133 BXGD000442 Carcinoma, Papillary Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011302 BXGD000711 Demyelinating disease of central nervous system Nervous System Diseases
C0011303 BXGD000712 Demyelinating Diseases Nervous System Diseases
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025267 BXGD001845 Multiple Endocrine Neoplasia Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Endocrine System Diseases
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0243010 BXGD005209 Viral Encephalitis Infections; Nervous System Diseases
C0262587 BXGD005259 Parathyroid Adenoma Neoplasms; Endocrine System Diseases
C0265962 BXGD005590 Ichthyosis linearis circumflexa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0276638 BXGD006435 Pseudoscarlatina Infections
C0278484 BXGD006511 Malignant neoplasm of colon stage IV Digestive System Diseases; Neoplasms
C0278488 BXGD006515 Carcinoma breast stage IV
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280220 BXGD006722 stage, ovarian epithelial cancer
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0521158 BXGD009130 Recurrent tumor
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699893 BXGD009871 Skin carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1266025 BXGD011935 Traditional Serrated Adenoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C1863051 BXGD016148 ALZHEIMER DISEASE 2 Nervous System Diseases; Mental Disorders
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3494652 BXGD018972 Severe dementia Nervous System Diseases; Mental Disorders
C3539781 BXGD019086 Progressive cGVHD
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4551463 BXGD023300 Colon adenoma Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein