Showing entry for Potassium voltage-gated channel subfamily B member 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019398
Protein NamePotassium voltage-gated channel subfamily B member 2
Uniport IdQ92953
GeneKCNB2
Gene Id9312
DomainBTB_2; Ion_trans; Kv2channel
Pfam PF02214   PF00520   PF03521  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0006940 regulation of smooth muscle contraction
molecular function GO:0005251 delayed rectifier potassium channel activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0005249 voltage-gated potassium channel activity
cellular component GO:0030425 dendrite
cellular component GO:0016021 integral component of membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296072 Voltage gated Potassium channels
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001948 BXGD000091 Alcohol consumption Behavior and Behavior Mechanisms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027902 BXGD002058 Neuropsychological Tests
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0518026 BXGD009069 body fat percentage (physical finding)
C1305855 BXGD012348 Body mass index
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047867 Dalfampridine 94.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein