Showing entry for U8 snoRNA-decapping enzyme


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019641
Protein NameU8 snoRNA-decapping enzyme
Uniport IdQ96DE0
GeneNUDT16
Gene Id131870
DomainNUDIX
Pfam PF00293  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa03018 RNA degradation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006382 adenosine to inosine editing
Biological Process GO:0035863 dITP catabolic process
Biological Process GO:0046709 IDP catabolic process
Biological Process GO:0006402 mRNA catabolic process
Biological Process GO:2000233 negative regulation of rRNA processing
Biological Process GO:0034656 nucleobase-containing small molecule catabolic process
Biological Process GO:0090068 positive regulation of cell cycle process
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:2000781 positive regulation of double-strand break repair
Biological Process GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Biological Process GO:0016077 snoRNA catabolic process
Biological Process GO:1901639 XDP catabolic process
molecular function GO:0031404 chloride ion binding
molecular function GO:0050897 cobalt ion binding
molecular function GO:0035870 dITP diphosphatase activity
molecular function GO:0005525 GTP binding
molecular function GO:0042802 identical protein binding
molecular function GO:1901641 ITP binding
molecular function GO:0050072 m7G(5')pppN diphosphatase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0008235 metalloexopeptidase activity
molecular function GO:0003729 mRNA binding
molecular function GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
molecular function GO:1990174 phosphodiesterase decapping endonuclease activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030515 snoRNA binding
molecular function GO:1901640 XTP binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins
R-HSA-74259 Purine catabolism
R-HSA-8956319 Nucleobase catabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0035613 BXGD002562 Rift Valley Fever Digestive System Diseases; Infections; Animal Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein