Showing entry for Histone-lysine N-methyltransferase PRDM9



                       
General Target Information
BXGT IdBXGT019653
Protein NameHistone-lysine N-methyltransferase PRDM9
Uniport IdQ96EQ9
GenePrdm9
Gene Id
DomainKRAB; SET; SSXRD; zf-C2H2
Pfam PF01352   PF00856   PF09514   PF00096  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990918 double-strand break repair involved in meiotic recombination
Biological Process GO:0007292 female gamete generation
Biological Process GO:0097676 histone H3-K36 dimethylation
Biological Process GO:0097198 histone H3-K36 trimethylation
Biological Process GO:0044648 histone H3-K4 dimethylation
Biological Process GO:0051568 histone H3-K4 methylation
Biological Process GO:0097692 histone H3-K4 monomethylation
Biological Process GO:0080182 histone H3-K4 trimethylation
Biological Process GO:0051567 histone H3-K9 methylation
Biological Process GO:0034968 histone lysine methylation
Biological Process GO:0016571 histone methylation
Biological Process GO:0048232 male gamete generation
Biological Process GO:0006311 meiotic gene conversion
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0016584 nucleosome positioning
Biological Process GO:1905516 positive regulation of fertilization
Biological Process GO:2001255 positive regulation of histone H3-K36 trimethylation
Biological Process GO:1905437 positive regulation of histone H3-K4 trimethylation
Biological Process GO:0060903 positive regulation of meiosis I
Biological Process GO:0010845 positive regulation of reciprocal meiotic recombination
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0007129 synapsis
molecular function GO:0018024 histone-lysine N-methyltransferase activity
molecular function GO:0042054 histone methyltransferase activity
molecular function GO:0046975 histone methyltransferase activity (H3-K36 specific)
molecular function GO:0042800 histone methyltransferase activity (H3-K4 specific)
molecular function GO:0046872 metal ion binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0010844 recombination hotspot binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
cellular component GO:0000785 chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein