Showing entry for OTU domain-containing protein 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019662
Protein NameOTU domain-containing protein 5
Uniport IdQ96G74
GeneOTUD5
Gene Id55593
DomainOTU
Pfam PF02338  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04622 RIG-I-like receptor signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032480 negative regulation of type I interferon production
Biological Process GO:0016579 protein deubiquitination
Biological Process GO:0071108 protein K48-linked deubiquitination
Biological Process GO:0070536 protein K63-linked deubiquitination
Biological Process GO:0032496 response to lipopolysaccharide
molecular function GO:1990380 Lys48-specific deubiquitinase activity
molecular function GO:0061578 Lys63-specific deubiquitinase activity
molecular function GO:0004843 thiol-dependent ubiquitin-specific protease activity
molecular function GO:0101005 ubiquitinyl hydrolase activity
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta
R-HSA-392499 Metabolism of proteins
R-HSA-5688426 Deubiquitination
R-HSA-5689896 Ovarian tumor domain proteases
R-HSA-597592 Post-translational protein modification
R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0027651 BXGD002009 Neoplasms Neoplasms
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030612 tetraethylene glycol 194.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein