protein

Showing entry for Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT019676
Protein Name	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
Uniport Id	Q96I99
Gene	SUCLG2
Gene Id	8801
Domain	ATP-grasp_2; Ligase_CoA
Pfam	PF08442 PF00549
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
1. Metabolism	1.1 Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)
1. Metabolism	1.1 Carbohydrate metabolism	hsa00640	Propanoate metabolism
1. Metabolism	1.0 Global and overview maps	hsa01100	Metabolic pathways
1. Metabolism	1.0 Global and overview maps	hsa01200	Carbon metabolism

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006105	succinate metabolic process
Biological Process	GO:0006104	succinyl-CoA metabolic process
Biological Process	GO:0006099	tricarboxylic acid cycle
molecular function	GO:0005524	ATP binding
molecular function	GO:0019003	GDP binding
molecular function	GO:0005525	GTP binding
molecular function	GO:0000287	magnesium ion binding
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0004775	succinate-CoA ligase (ADP-forming) activity
molecular function	GO:0004776	succinate-CoA ligase (GDP-forming) activity
cellular component	GO:0005759	mitochondrial matrix
cellular component	GO:0005739	mitochondrion
cellular component	GO:0005886	plasma membrane
cellular component	GO:0042709	succinate-CoA ligase complex
cellular component	GO:0045244	succinate-CoA ligase complex (GDP-forming)

Reactome

Pathway Id	Pathway Name
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport
R-HSA-1430728	Metabolism
R-HSA-71403	Citric acid cycle (TCA cycle)
R-HSA-71406	Pyruvate metabolism and Citric Acid (TCA) cycle

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0005890	BXGD000345	Body Height
C0014175	BXGD000904	Endometriosis	Female Urogenital Diseases and Pregnancy Complications
C0016529	BXGD001068	Forced expiratory volume function
C0023467	BXGD001658	Leukemia, Myelocytic, Acute	Neoplasms
C0028754	BXGD002082	Obesity	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0042834	BXGD003004	Vital capacity
C0152013	BXGD003516	Adenocarcinoma of lung (disorder)	Neoplasms
C0234985	BXGD004708	Mental deterioration	Mental Disorders
C0268583	BXGD005997	Methylmalonic acidemia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0269102	BXGD006053	Endometrioma	Female Urogenital Diseases and Pregnancy Complications
C0338656	BXGD007211	Impaired cognition	Mental Disorders
C0489786	BXGD009018	Height
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C1261502	BXGD011856	Finding of Mean Corpuscular Hemoglobin
C1855119	BXGD015463	Methylmalonic aciduria	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002953	2-Phenethyl isothiocyanate		163.24

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}