protein

Showing entry for CCR4-NOT transcription complex subunit 6-like

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT019694
Protein Name	CCR4-NOT transcription complex subunit 6-like
Uniport Id	Q96LI5
Gene	CNOT6L
Gene Id	246175
Domain	Exo_endo_phos; LRR_8
Pfam	PF03372 PF13855
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
2. Genetic Information Processing	2.3 Folding, sorting and degradation	hsa03018	RNA degradation

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Biological Process	GO:0031047	gene silencing by RNA
Biological Process	GO:0061157	mRNA destabilization
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
Biological Process	GO:0008284	positive regulation of cell population proliferation
Biological Process	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
molecular function	GO:0000175	3'-5'-exoribonuclease activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004535	poly(A)-specific ribonuclease activity
cellular component	GO:0030014	CCR4-NOT complex
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name
R-HSA-212436	Generic Transcription Pathway
R-HSA-3700989	Transcriptional Regulation by TP53
R-HSA-429914	Deadenylation-dependent mRNA decay
R-HSA-429947	Deadenylation of mRNA
R-HSA-6791312	TP53 Regulates Transcription of Cell Cycle Genes
R-HSA-6804115	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
R-HSA-73857	RNA Polymerase II Transcription
R-HSA-74160	Gene expression (Transcription)
R-HSA-8953854	Metabolism of RNA

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0079744	BXGD003090	Diffuse Large B-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002588	Magnesium		24.31
BXGC0024261	Adenosine Phosphate		347.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}